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Different kinds of cargoes carried by EVs are major drivers in their regulatory effects [96, 97]

Equine Reproduction 2nd edn (Wiley, 2011)

Verdan MH, Stefanello MA (2012) Secondary metabolites and biological properties of Gesneriaceae species

A number of other studies 7 have shown that NAC can help to decrease: BMI, which means NAC weight loss may be at play Hirsutism (meaning there was less hair on the face, chest, and abdomena common complaint of women with PCOS) Fasting insulin (there was better blood sugar balance) Free testosterone (unusually high levels of testosterone can lead to acne, oily skin, and hair loss) Menstrual irregularities Total and LDL cholesterol (Metformin only led to a decrease in total cholesterol) In my clinical practice, I've had patients experience these types of benefits while taking 900 mg twice daily

Consequently, the future of FRDA therapeutics inevitably points toward combinatorial strategies